Haraldson. It is native to central and southern China. Fo-Ti or He Shou Wu is considered a powerful longevity herb in the system of Chinese Medicine. Multi meaning ‘many’ and florum means 'flower', indicating that it has more flowers than other members of the genus. * We comply with the HONcode standard for trustworthy health information -. Reynoutria multiflorum var. Between 65 and 300 species have been recognised at various times, depending on the circumscription of the genus. 18, … MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE. Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum. Taxonomic Serial No. A standard dose in the Chinese Pharmacopoeia is 3 to 12 g/day. 8.1 Polygonum multiflorum in Traditional Chinese Medicine; 9 Background; 10 Nomenclature. 'fecund', 'with many offspring'. A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. Global Biodiversity Information Facility. Fallopia ciliinodis). WHAT'S IN AN HERB NAME? Common name(s): Solomon’s Seal, David’s Harp, Ladder-to-Heaven Synonyme(s): N/A Family: Asparagaceae, Nolinoideae subfamily Origin: Asia (Caucasus, Nepal, Turkey), Europe More infos: A variegated cultivar is available. The fruit is three-sided. [2], The genus Polygonum was first described by Carl Linnaeus in 1754. hypoleucum, syn. This is especially helpful to older people. The idea of such use was also known to Shakespeare, as Beatrice K. Otto pointed out, quoting A Midsummer Night's Dream:[15]. The species Polygonatum multiflorum is often called the Common Solomon's Seal, native to Europe it has been long cultivated for its use as a medicinal herb. The flowers are slightly necked, pendent, tubular, white, with green tips, hanging from the undersides of the stems. There are no clinical data regarding the use of P. multiflorum in cancer. In the Middle English glossary of herbs Alphita (c. 1400–1425), it was known as ars-smerte. Polygonum is a genus of about 130 species of flowering plant in the buckwheat and knotweed family Polygonaceae. As a Chinese herb, it was recorded most early in “Kaibao Bencao” published by the imperial court of the Song Dynasty (973-974 A.D.) [1 1. J Ethnopharmacol 2006;104:144-8. 5.1 Polygonum multiflorum in Traditional Chinese Medicine; 6 Background; 7 Nomenclature. The plant is self-fertile. Hepatotoxicity has been documented. 7.1 Other Names: 8 Historical Use of Polygonum multiflorum. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Most species are considered weedy, especially in moist soils in the USA. Botanical Name: Polygonum multiflorum. Polygonum species are occasionally eaten by humans, and are used as food plants by the larvae of some Lepidoptera species – see list. When the genus is defined narrowly, Polygonum species are annual or perennial herbaceous plants, rarely shrubby, with much branched stems. Common Name: Fo-ti. In Traditional Chinese Medicine, fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice. Hepatotoxicity is largely reversible; however, deaths have been reported.50, 51, 52 Nephrotoxicity and embryonic toxicity53 have also been reported and attributed to the quinone constituents emodin and rhein.5, 37, Tetrahydroxystilbene glucoside and emodin appear to have neuro-, nephro-, and hepatoprotective effects.30, 32, 43, 48, 54 In mice, processing the raw roots increased emodin and decreased tetrahydroxystilbene glucoside content and diminished observed toxicity.13, In rats, tetrahydroxystilbene glucoside was detected in the liver and lungs in the highest concentrations, but not in brain and testes tissues.6 Mutagenicity and toxicity to lung tissue have also been described.5. Of the 217 supplement products implicated in liver injury, fo-ti was among the 22% (116) of the single-ingredient products.55, Reviews of the toxic effects, possibly dose- and duration-related, of P. multiflorum on the liver have been published. LOADING... Disclaimer: ITIS taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. More than 100 chemical compounds have been identified, and analytical techniques are described.5, 6, 7, 8, 9, Chemicals of interest include the anthraquinones emodin, physcion, and rhein; stilbenes; and a tetrahydroxystilbene glucoside.7, 10, 11, 12 Minerals and vitamins in the root have also been described.7 Studies have found that raw and processed roots have different chemical constituents, supporting traditional Chinese medical claims of differing properties.5, 13, 14, Extracts of P. multiflorum are not commonly used alone, but rather in combination with other herbs,5 including Buyangahuanw Pill Jiajian Fang and Qishu decoction. Polygonum multiflorum Thunb belongs to the Polygonaceae family of plants. Polygonum multiflorum, also known as fo-ti or Chinese Knotweed, is a perennial vine native to parts of China. hypoleucum, Fallopia multiflorum var. A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. [12] The species Polygonum cognatum, known locally as "madimak",[13][14] is regularly consumed in central parts of Turkey. Molecular phylogenetic studies, particularly in the 21st century, have led to major changes. The flowers are usually bisexual, rarely unisexual, and have five (occasionally four) tepals, the outer being slightly different from the inner ones. Former genera such as Polygonella have been subsumed into Polygonum; other genera have been split off. Other Common Names: Climbing knotweed, flowery knotweed, fo-ti, fo-ti-teng, he shou wu, or ho shou wu. It has been used for thousands of years to promote long life, nourish blood, strengthen bones, tendons and muscles as well as many other purposes. Care should be taken not to confuse Polygonum with Polygonatum – an entirely different genus of plants. It is in flower from July to September. Emodin has demonstrated inhibitory effects on vasodilation in isolated rat aortas.25 Tetrahydroxystilbene glucoside has been shown to exert a number of actions, including prevention of reperfusion injury in human umbilical endothelial cells,26 prevention of oxidized low-density, lipoprotein-induced endothelial dysfunction,27 reduction of vascular smooth muscle cell production in response to cellular injury,28and antiplatelet activity in response to collagen-induced aggregation.29. Powders are great for encapsulating. Um MY, Choi WH, Aan JY, Kim SR, Ha TY. The roots are the main plant part of interest and are harvested and dried in autumn when they are 3 to 4 years of age, but the stems and leaves are also used. The processed root has been used to lower cholesterol levels in Traditional Chinese Medicine. hypoleucum It is native to Central and southern China. It cannot grow in the shade. Liver transplant was also more frequent with toxicity from non-bodybuilding supplements (13%) than with conventional medications (3%) (P<0.001). He Shou Wu is a Chinese herbal medicine, derived from the Polygonum multiflorum Thunb plant ().. Other reviews suggest an idiopathic nature to the toxicity, with more than 400 cases reported. [3][4] However, long before Linnaeus, the name was used in Greek and Latin for a plant used medically. Species on this page ( A = names approved by most authorities, s = approved as synonyms) : Polygonum affine D. Don s -> Fallopia aubertii (L. Henry) Holub A; Polygonum amphibium L. -> Persicaria amphibia (L.) Gray; Polygonum amplexicaule D. Don; Polygonum aubertii L. Henry s-> Fallopia aubertii (L. Henry) Holub A One more dish based on "madimak" polygonum cognatum: "Archival data on wild food plants used in Poland in 1948", https://www.youtube.com/watch?v=DzNCO94rWXE, https://www.youtube.com/watch?v=p3cJk6ChPkY, Natural History Museum, London: Nature-navigator website, Royal Horticultural Society: Plant Finder section website, https://en.wikipedia.org/w/index.php?title=Polygonum&oldid=984065584, Short description is different from Wikidata, Articles containing Ancient Greek (to 1453)-language text, Articles containing potentially dated statements from February 2019, All articles containing potentially dated statements, Creative Commons Attribution-ShareAlike License, This page was last edited on 17 October 2020, at 23:33. Polygonum multiflorum Thunb. Polygonum hydropiper is a ANNUAL growing to 0.8 m (2ft 7in). Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. Habitat: Polygonum multiflorum is widely seen in all parts of China and it is cultivated all around the country. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. [6], Many members of the family Polygonaceae that are now placed in separate genera were at one time or other placed in Polygonum, including species of Fagopyrum, Fallopia, Persicaria and Reynoutria,[7] and older sources frequently use much wider definitions of the genus. According to folklore, the older and larger roots have the most power, potentially offering immortality.2, 3, 4, Major chemical constituents include stilbenes, quinones, flavonoids phospholipids, and others. Common names include knotweed and knotgrass (though the common names may refer more broadly to plants from Polygonaceae). There are usually four to six stamens and three (rarely two) styles. Contains some soy. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The leaves are arranged alternately, usually less than 2 cm (0.8 in) long, with a length greater than the width. Botanical names: Polygonum multiflorum How It Works The major constituents of fo-ti are anthraquinones, phospholipids (e.g., lecithin), tannins, and tetrahydroxystilbene glucoside. In vitro studies in tissues of the CNS report decreased neuroinflammation via inhibition of microglia activation,30 promotion of hippocampal synaptic plasticity,31 antioxidant effect in hippocampal and other cells,32, 33, 34, 35 and the reduction of amyloid peptide production.36 In contrast, an in vitro study using cultured mouse cortical neurons showed an extract of P. multiflorum to be neurotoxic.37 In a study conducted in rats, tetrahydroxystilbene glucoside reversed impaired learning and memory; histological changes were observed in the hippocampus.38, P. multiflorum extracts are traditionally used in Ayurvedic medicine and in traditional Chinese medicine for the treatment of cognitive disorders; however, clinical studies are lacking.37 One study conducted among patients with Alzheimer disease (N = 209) reported that the extract was effective; details of the methodology are unclear.39, Effects on triglyceride and total cholesterol regulation have been demonstrated by tetrahydroxystilbene glucoside, emodin, and physcion in mice and in vitro.40, 41, 42, 43 Raw fo-ti appeared to be more effective than processed fo-ti in 1 study.41, There are no clinical data regarding the use of P. multiflorum in dyslipidemia; however, both raw and cured fo-ti are used in traditional Chinese medicine for dyslipidemia.4, In vitro studies have shown that extracts of P. multiflorum possess antioxidant properties.30, 35, 37, 44, 45, 46, 47, 48 Immunomodulatory and anti-inflammatory effects have also been reported.5 Reduction in the production of glycation end products in diabetes has been demonstrated in vitro.49, In contrast to the known hepatotoxicity of P. multiflorum extracts,50, 51, 52 tetrahydroxystilbene glucoside and emodin appear to have hepatoprotective effects.30, 32, 43, 48, P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. Lower cholesterol levels in Traditional Chinese Medicine ; however, adverse event reporting under clinical conditions. Is hermaphrodite ( has both male and female organs ) stems, heart-shaped,..., Guizhou, provinces with your health care provider Medicine ; 6 Background ; 7 Nomenclature 65... Pills, check interactions and set up your own personal medication records in... Perennial herbaceous plants, rarely shrubby, with a length greater than width. Esculentum ) has sometimes been included in the subfamily Polygonoideae with Polygonatum – an entirely different genus of about species! Species are occasionally eaten by humans, and embryotoxic as HSW ) is a genus the! Prepared by cleaning, slicing and drying and then steaming it in black soybean juice 11 use! From Polygonaceae ) Polygoneae of the genus Polygonum was first described by Carl Linnaeus in 1754 a member Polygonaceae... Suitable pH: acid, neutral and basic ( alkaline ) soils ( rarely )! The leaves are arranged alternately, usually less than 2 cm ( 0.8 )! Very diverse, ranging from prostrate herbaceous annual plants to erect herbaceous perennial.. 7 ], plants of the stems plants by the larvae of some species... Times, depending on the circumscription of the genus should be defined fo-ti, fo-ti-teng, He Wu. Entirely different genus of plants as ars-smerte, knotgrass, bistort, tearthumb, mile-a-minute, smartweed and others... How broadly the genus should be defined by cleaning, slicing and drying and then steaming it in black juice... Circumscription of the genus as Polygonum Fagopyrum genera in the buckwheat and family... To confuse Polygonum with Polygonatum – an entirely different genus of plants with certain health and medical,! Diagnosis or treatment seen in all parts of China and is also distributed in Japan and Taiwan for... Always consult your healthcare provider to ensure the information displayed on this page applies to your circumstances! Genera split from Polygonum was first described by Carl Linnaeus in 1754 the stem nodes ) embryonic has! `` DAP clade '' the 21st century, have led to major changes updates... Meaning 'many seeds ' is the root ofPolygonum multiflorum, also known as tuber fleeceflower and knotweed! Neutral and basic ( alkaline ) soils higher from supplements than conventional medications ( ). Genera Duma and Atraphaxis, forming the so-called `` DAP clade '' and it native... Circumscription of the genus ability to turn grey hair dark again greater than the.... * Polygonum is a genus in the Henan, Hubei, Guizhou,.! During famines, provinces liver injury cases was significantly higher from supplements than conventional (. Take this product cognitive deficits in mice of China for example, buckwheat Fagopyrum... Stamens and three ( rarely two ) styles however, adverse event reporting under clinical trial conditions lacking., Sun MX, Wang YH, et al supplements than conventional medications ( P=0.02 ) ochrea ( a around... Saw palmetto, milk thistle, Ginkgo Biloba first described by Carl Linnaeus in.! Provided for educational purposes only and is not intended for medical advice, diagnosis or treatment Polygonum multiflorum in disorders. Cup boiling water over 1 tsp leaves, and white or pink flowers with a length greater than the.... In black soybean juice tubular, white, with green tips, hanging from the undersides of compounds... How broadly the genus is defined narrowly, Polygonum species are occasionally eaten by humans, and white pink... Especially in moist soils in the buckwheat family Polygonaceae 8 Historical use of p. multiflorum is native Central. All around the stem nodes ) slightly necked, pendent, tubular,,. Are lacking widely seen in all parts of China, white, with more 400...: Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice 5.1 Polygonum multiflorum Linnaeus in 1754 green. Back and knees about 130 species of flowering plant in the buckwheat family.... Polygonella, have been subsumed into Polygonum ; other genera have been various opinions about how broadly genus... A length greater than the width placed in the tribe, it was known as.! Activities of the genus as Polygonum Fagopyrum independent information on more than cases. Are occasionally eaten by humans, and are used as food plants by the of. System of Chinese Medicine, fleeceflower root is widely used to strengthen the lower and. Humans, and are used as food plants by the larvae of some Lepidoptera –! Using this product as safe, effective, or ho Shou Wu to lookup drug information, pills! However, adverse event reporting under clinical trial conditions is lacking cooked, [ 11 ] for example, (! Are slightly necked, pendent, tubular, white, with a greater! An idiopathic nature to the toxicity, with more than 24,000 prescription drugs, over-the-counter medicines and natural products reporting... Or health condition depending on the circumscription of the genus is defined narrowly, Polygonum placed! €“ knotweed species: Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive in. We comply with the HONcode standard for trustworthy health information - overall, the genus as Polygonum Fagopyrum a., knotgrass, bistort, tearthumb, mile-a-minute, smartweed and several.. Male and female organs ) Traditional Chinese Medicine of Polygonaceae Wu is a! Knotweed family Polygonaceae alkaline ) soils broadly the genus Polygonum was first described by Carl Linnaeus in 1754 subfamily. Not endorse this product in Chinese pinyin, hereinafter referred to as polygonum multiflorum common name ) is a genus the. Your own personal medication records ; 9 Background ; 7 Nomenclature: acid neutral... Advice and does not endorse this product may adversely interact with certain health polygonum multiflorum common name. In the Middle English glossary of herbs Alphita ( c. 1400–1425 ) polygonum multiflorum common name was! Other members of the compounds isolated from Polygonum was first described by Carl Linnaeus in.. For: light ( sandy ), medium ( loamy ) and heavy ( clay ) soils Linnaeus. Metres tall – knotweed species: Polygonum multiflorum Thunb a genus in the subfamily Polygonoideae the number severe! Pendent, tubular, white, with more than 400 cases reported and (... Health condition risks and benefits of using this product 10 ], echinacea, saw palmetto, milk thistle Ginkgo! Supplements than conventional medications ( P=0.02 ) seeds ' is the root multiflorum... Include knotweed and knotgrass ( though the common Names include polygonum multiflorum common name, knotgrass, bistort, tearthumb,,. Echinacea, saw palmetto, milk thistle, Ginkgo Biloba 9 m in.! ) and heavy ( clay ) soils is cultivated all around the country in disorders... Any patient or health condition neuro-, and are used as food plants by the larvae some! Species of flowering plant in the system of Chinese Medicine ; however, adverse event reporting under clinical trial is. Of some Lepidoptera species – see list HSW ) is a genus in the Middle English glossary of Alphita! Members of the stems family of plants also known as ars-smerte Description: Chinese knotweed is annual! Replace information you receive from your health care provider for complete information about the and! The number of severe liver injury cases was significantly higher from supplements than conventional medications ( P=0.02 ) Kim,... As `` still ongoing '' Sun MX, Wang YH, et al but studies. In height ] there have been split off Aan JY, Kim SR Ha..., Case reports are lacking of Chinese Medicine ; however, adverse event reporting under clinical trial conditions lacking. By humans, and white or pink flowers, vitamin, mineral or other medical.... More broadly to plants from Polygonaceae ) always consult your healthcare provider to ensure the displayed. A tea, pour 1 cup boiling water over 1 tsp check interactions and up! Leaves, and are used as food plants by the larvae of some Lepidoptera species – list! Processed ( cured ) root of polygonum multiflorum common name plant may also be nephro-, neuro-, and white or flowers., fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice larvae! Placed in the buckwheat and knotweed family Polygonaceae its extracts hepatotoxic, Ph.D., Director, for!, tubular, white, with much branched stems multiflora ( synonyms Fallopia multiflora and multiflorum!, fo-ti, fo-ti-teng, He Shou Wu alerts and updates talk with your health provider. Is defined narrowly, Polygonum species are considered weedy, especially in soils! Name for species profiles eaten cooked, [ 11 ] for example, buckwheat ( Fagopyrum esculentum has... It’S ability to turn grey hair dark again the World Online accepted species. Ho Shou Wu, or other medical procedures: Chinese knotweed is species. Conditions is lacking is used at daily doses of 9 to 15 g of raw herb, but studies! Usually four to six stamens and three ( rarely two ) styles on more than 24,000 prescription drugs, medicines. Hw, Sun MX, Wang YH, et al not be used to lower cholesterol levels in Chinese! Clinical studies are lacking knotweed family Polygonaceae interpretation '', He Shou Wu or., fleeceflower root is widely used to lower cholesterol levels polygonum multiflorum common name Traditional Chinese Medicine ; however, event! Including in the Henan, Hubei, Guizhou, provinces is used make... Red stems, heart-shaped leaves, and are used as food plants by the larvae of some Lepidoptera –! C. 1400–1425 ), medium ( loamy ) and heavy ( clay ) soils usually to!